An unusual cause of severe, persistent diarrhoea
| Journal | Volume 80 - 2017 |
| Issue | Fasc.3 - Case reports |
| Author(s) | Bram Verstockt, Barbara Deleenheer, Filip Sermon, Kris Van Der Steen, Jo Vandervoort |
| Full article |
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| (1) Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium ; (2) Translational Research in Gastrointestinal Disorders (TARGID), Department of Clinical and Experimental Medicine, KU Leuven, Leuven, Belgium ; (3) Department of Gastroenterology, O.L.V. Hospitals Aalst, Asse, Ninove, Belgium ; (4) University Hospitals Leuven, Belgium, Pharmacy Dept. & KU Leuven, Belgium, Dept. of Pharmaceutical and Pharmacological Sciences ; (5) O.L.V. Hospital, Aalst, Belgium, Dept. Pathology. |
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We present two cases of patients with severe persistent diar- rhoea, in whom duodenal biopsies revealed villous atrophy that could be attributed to the use of olmesartan. The differential diagnosis of villous atrophy without serological markers of celiac disease should include drugs as possible cause, with olmesartan as a recently discovered culprit. Gastroenterologist should be aware of this entity. (Acta gastroenterol. belg., 2017, 80, 416-418). |
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© Acta Gastro-Enterologica Belgica. PMID 29560673 |
